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评估新的抗菌素西利用于对抗梨花的火灾病

Jiuxiang Zhu ^1,2, Ling Cai ^1,2, Yixin Wang ^1,2

¹College of Plant Protection and Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing Agricultural University, Nanjing, 210095, China.
²Key Laboratory of Plant Quarantine Pests Monitoring and Control, Ministry of Agriculture and Rural Affairs, Nanjing, 210095, China.
³Plant Protection and Quarantine Station of Xinjiang Province, Urumqi, 830001, China.
⁴College of Plant Protection and Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing Agricultural University, Nanjing, 210095, China. tianyanli@njau.edu.cn.
⁵Key Laboratory of Plant Quarantine Pests Monitoring and Control, Ministry of Agriculture and Rural Affairs, Nanjing, 210095, China. tianyanli@njau.edu.cn.
⁶College of Plant Protection and Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing Agricultural University, Nanjing, 210095, China. hbs@njau.edu.cn.
⁷Key Laboratory of Plant Quarantine Pests Monitoring and Control, Ministry of Agriculture and Rural Affairs, Nanjing, 210095, China. hbs@njau.edu.cn.
⁸Xinjiang Key Laboratory of Agricultural Biosafety, Urumqi, 830013, China. hbs@njau.edu.cn.
⁹College of Agriculture, Xinjiang Agricultural University, Urumqi, 830052, China. hbs@njau.edu.cn.
¹⁰Plant Pathology Department, Endowed Chair in Bacterial Diseases of Tree Fruits, Washington State University, Prosser, WA, 99350, USA.

⁰College of Plant Protection and Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing Agricultural University, Nanjing, 210095, China.

Bmc Microbiology +

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2025年八月23日

在PubMed上查看摘要

概括

在实地试验中,本齐利能有效控制果和梨的火灾. 这种新型杀菌剂具有较低的耐药性风险,

科学领域

植物病理学
农业微生物学
有机化学

背景情况

果和梨的作物受到火灾的破坏,
由于抗生素耐药性和化学残留问题,现有的疾病管理策略面临挑战.
在中国注册了一种新型杀菌剂benziothiazolinone (1,2-Benzisothiazol-3-one).

研究的目的

评估西利作为抗菌剂的功效.
评估西利的抗菌谱和致病性.
为了确定本齐奥提亚索林的耐药性风险和现场性能,以防火灾.

主要方法

在体外测试西利对Erwinia amylovora菌株的敏感性.
对各种微生物进行更广泛的抗菌谱分析.
病原性测定和氨酸生产评估.
阻力风险分析和为期两年的实地试验,以减少火灾的发生率.

主要成果

西利对E. amylovora具有强烈的活性,EC50值为0. 48μg/ mL (10小时) 和0. 67μg/ mL (16小时).
这种化合物表现出广泛的抗菌作用,尽管增强了氨酸的产生,但显著降低了病原性.
实地试验证实了80%以上的降低火灾发病率的有效性,与杆菌素相比,耐药性发展的风险较低.

结论

西利是一种高效的杀菌剂,可对抗Erwinia amylovora.
它具有较低的耐药性和广泛的抗菌活性风险.
西利是一种有前途的农业化学品,可用于梨和果种植的可持续火灾防治.

关键词:

抗菌药物西奥提亚索林火灾伤害

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