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Updated: Sep 10, 2025

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
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通过多尺度模拟揭示了RAS-RAF复合物的动力学和脂质膜合

Timothy S Carpenter1, Fikret Aydin1, Chris Neale2

  • 1Physical and Life Sciences (PLS) Directorate, Lawrence Livermore National Laboratory, Livermore, California.

Biophysical journal
|August 24, 2025
PubMed
概括

膜环境通过在RAS-RBDCRD蛋白质复合体周围形成不同的脂质安排来影响RAS-RAF信号复合体的形成. 这些特定的膜相互作用增加了信号复杂组合的概率.

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