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Updated: Sep 10, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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卡尔帕因-1,而不是卡尔帕因-2,与多发性硬化症中的HMGB1/TLR4/NF-KB信号通路变量有关

Firdevs Uluc1, Sule Aydin Turkoglu2, Bihter Gokce Celik1

  • 1Department of Interdisciplinary Neuroscience, Institute of Health Sciences, Bolu Abant İzzet Baysal University, Bolu, Turkey.

Neurological research
|August 24, 2025
PubMed
概括

在患有多发性硬化症 (MS) 和神经脊髓炎光谱障碍 (NMOSD) 的患者中,Calpain- 1和Calpain- 2水平升高,这表明它通过HMGB1途径在神经炎症中起作用.

关键词:
卡尔帕因-1卡尔帕因-2多发性硬化症高流动性组第1框视神经炎光谱障碍

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