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相关概念视频

Quantifying Work02:30

Quantifying Work

As a system undergoes a change, its internal energy can change, and energy can be transferred from the system to the surroundings, or from the surroundings to the system.
Distributed Loads01:19

Distributed Loads

Distributed loads are a common type of load that engineers and scientists encounter in various practical situations. Distributed loads often refer to a type of load spread over a surface or a structure and can be modeled as continuous force per unit area.
For example, consider a bookshelf filled with books stacked vertically adjacent to each other. The weight of the books is evenly distributed over the length of the shelf. As a result, the pressure at different locations on the surface of the...
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Distribution Reliability and Automation

Distribution reliability in electrical power systems is critical for ensuring an uninterrupted power supply to consumers at minimal cost. According to IEEE Standard Terms, reliability is the probability that a device will function without failure over a specified time period or amount of usage. For electric power distribution, this translates to maintaining continuous power supply and addressing customer concerns over power outages. Several indices, as defined by IEEE Standard 1366-2012, are...
Flow Table Test01:12

Flow Table Test

The flow table test is an established method used to assess the workability of concrete, particularly useful for evaluating highly flowable concrete mixes. This test employs an apparatus that consists of a wooden board topped with a steel plate, collectively weighing 35 pounds. The board is connected to a base via a hinge and measures 27.6 inches on each side.
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Run Charts

Run charts serve as an essential instrument for visualizing the performance of various processes over time, enabling the identification of trends and patterns crucial for quality improvement. These charts map out a series of data points chronologically, offering insights into the stability and efficiency of a process. A run chart's creation involves plotting data points on a graph, with the time intervals on the horizontal axis and the specific measurements on the vertical axis. For example,...
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Scale-Up Processes

The scale-up of microbial fermentation processes is essential in industrial biotechnology, allowing the transition from laboratory-scale experiments to commercial-scale production while aiming to maintain product yield and quality. This process requires meticulous adjustment of equipment design, process parameters, and contamination control strategies to accommodate increasing culture volumes.At the laboratory scale, cultures are typically maintained in 1 to 10-liter glass or autoclavable...

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相关实验视频

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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
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开发和演示端到端测试的分数内运动管理的工作流程

Stijn Oolbekkink1, Jochem W H Wolthaus1, Bram van Asselen1

  • 1Department of Radiotherapy, University Medical Center Utrecht, Utrecht, the Netherlands.

Medical physics
|August 24, 2025
PubMed
概括

使用运动包含剂量分布开发了用于端到端测试分数内运动控制的工作流程的新方法. 这些新方法,APriMI和PostMI,可以通过实时运动补偿来准确评估治疗的准确性.

科学领域:

  • 医学物理
  • 辐射瘤学
  • 图像指导治疗

背景情况:

  • 在MR-linacs上使用分量内运动管理技术 (光束隔离,分量内偏移校正) 来减少运动的剂量影响.
  • 剩余运动可能导致规划剂量的偏差,常规端到端 (E2E) 测试不考虑这种已知的运动.
  • 这限制了动作管理工作流程的准确性评估.

研究的目的:

  • 开发和展示用于E2E测试的参考剂量分布中已知运动的新方法.
  • 为了能够准确的E2E测试分数内运动管理的工作流程.

主要方法:

  • 开发了包括运动在内的两个参考剂量分布:包括运动在内的先验 (APriMI) 和包括运动在内的后期 (PostMI).
  • APriMI使用已知的周期性运动来估计和结合运动对剂量的影响;PostMI使用外部触发器来与非周期性或漂移运动的运动相关联.
  • 在使用膜剂量计的Unity MR-linac上评估静态,无控制和运动控制 (Gated,IDC) 场景,将测量剂量与静态,APriMI和PostMI参考值进行比较.

主要成果:

  • 在静态基准场景中,测量剂量与参考剂量之间存在很高的一致性.
  • 在使用APriMI或PostMI (几何偏移<0. 3mm,玛指数>95. 5%) 的运动包含场景中,测量剂量和计算剂量之间观察到很好的一致性.
关键词:
核磁共振指导放射治疗端到端测试在分数内进行运动管理

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  • 使用静态剂量分布作为参考结果导致显著的偏差 (几何偏移高达9. 0毫米,马传递率低至17. 8%).

    • 结论:

    • APriMI和PostMI的剂量分布使得E2E可以有效地测试分数内运动控制的工作流程.
    • 与静态参考不同的是,运动包含的参考剂量分布与测量结果有很强的一致性.
    • 准确评估E2E的准确性需要在治疗过程中包含实际运动的参考剂量文件.