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用于热除的光谱计算机断层测量:适用性和针缩小
Lennart R Koetzier1, Pim Hendriks2, Jan W T Heemskerk2
1Department of Radiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZG Leiden, the Netherlands; Department of Radiation Science and Technology, Delft University of Technology, Mekelweg 5, 2628 CD Delft, the Netherlands.
概括
光谱CT温度计可以精确监测微波除温度, 基于物理密度的光谱CT温度计与O-MAR相结合,可提高肝脏瘤切除的准确性和可重复性.
科学领域:
- 医学成像
- 干预性放射学
- 癌症学
背景情况:
- 精确监测热除区域对于有效治疗肝脏瘤至关重要.
- 计算机断层扫描 (CT) 温度测量提供了非侵入性温度监测,但被除设备的金属工件所阻碍.
研究的目的:
- 评估光谱CT温度计用于微波除监测.
- 为了比较基于衰减和基于物理密度的温度计的可复制性,精度和准确性.
- 确定最佳的金属工件减少 (MAR) 方法,包括O-MAR和深度学习-MAR.
主要方法:
- 在微波除过程中对凝幻体进行双层光谱CT成像.
- 基于衰减和物理密度的温度图的重建.
- 对温度计模型的可复制性和准确性进行评估.
- 应用MAR技术来评估受工件影响的切片的温度精度.
主要成果:
- 在CT值和温度之间具有很高的线性 (R平方>96%).
- 物理密度图在存在针件时提高了73%的温度精度.
- 与没有MAR相比,O-MAR提高了49%的温度精度.
- 基于减弱的温度计显示比基于物理密度的温度计更窄的Bland-Altman协议极限.
结论:
- 基于光谱物理密度的CT温度计在150keV时,使用O-MAR,在金属工件存在时提高温度精度.
- 这种方法可以实现可重复和准确的温度测量,以监测肝脏瘤的移除.
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