脱水和中风之间的关联,大数据库的回顾性队列研究
Irene Hamrick1, Wen-Jan Tuan2, Pablo Harker3
1University of Cincinnati, College of Medicine, Department of Family and Community Medicine, Division of Geriatrics, Cincinnati, Ohio.
概括
脱水会显著增加老年人中风的风险,尤其是脑内出血. 这项研究强调了饮水对于预防老年人中风的重要性.
科学领域:
- 老年学
- 神经学
- 公共卫生
背景情况:
- 年龄增长与老年人脱水风险增加有关.
- 在老年人群中, 脱水是常见的问题.
- 研究脱水与中风之间的联系对于老年人的健康至关重要.
研究的目的:
- 在80岁及以上的成年人中确定脱水和中风之间的联系.
- 分析脱水的老年人中风风险,包括糖尿病患者.
- 确定与脱水最密切相关的特定类型的中风.
主要方法:
- 使用TrinetX电子健康记录数据库进行的回顾性队列研究 (超过8500万患者).
- 包括在2018年1月至2019年12月期间接受过医疗服务的80岁以上的成年人.
- 通过ICD-10代码和实验室结果识别的脱水;基于ICD-10代码的中风类型 (脑内出血,缺血中风,TIA).
主要成果:
- 分析了超过310万名成年人 (80岁以上);563,476人脱水.
- 脱水的人患中风的可能性是1.98至3.99倍.
- 这种关联在脑内出血方面最为强烈 (OR=3. 99),而糖尿病则增加了这种风险 (OR=6. 76).
结论:
- 在老年人中脱水和中风之间存在显著的联系.
- 脑内出血与脱水有着最强烈的联系.
- 需要进一步研究水分对预防中风的作用.
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