Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

200
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
200
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

419
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
419
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

145
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
145

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Clinical care site data integration reveals heterogeneity in EHR phenotyping and healthcare utilization patterns.

medRxiv : the preprint server for health sciences·2026
Same author

Increased Arrhythmic Risk in Obesity Is Transduced by Adipose Tissue-Derived Extracellular Vesicles.

JACC. Basic to translational science·2026
Same author

Surgical and clinical predictors of successful Hartmann reversal procedure after perforated diverticulitis.

Surgical endoscopy·2026
Same author

Endoscopic recurrence of Crohn's disease following laparoscopic versus robotic ileocolic resection.

Techniques in coloproctology·2026
Same author

Genetically predicted cytotrophoblast gene expression is associated with birth weight and adult body mass index.

Placenta·2026
Same author

Harnessing Polygenic Risk Scores to Refine Venous Thromboembolism Risk Stratification.

European journal of haematology·2026
Same journal

Survival Following Neoadjuvant Chemoradiation in Rectosigmoid Junction Adenocarcinoma: SEER Analysis.

The Journal of surgical research·2026
Same journal

Operative Case Trends in General Surgery Residency: Growth Across All Levels.

The Journal of surgical research·2026
Same journal

The Plantaris Tendon in Surgery: A Scoping Review of Reconstructive Roles Beyond Orthopedics.

The Journal of surgical research·2026
Same journal

Open Versus Minimally Invasive Surgery for Congenital Diaphragmatic Hernia Repair: A Systematic Review and Meta-analysis.

The Journal of surgical research·2026
Same journal

Time-resolved Impact of Smoke Evacuation on Particulate Exposure During Laparoscopic Cholecystectomy.

The Journal of surgical research·2026
Same journal

Geriatric Age is an Independent Risk Factor for Worse Clinical Outcomes After Motorcycle Collision.

The Journal of surgical research·2026
查看所有相关文章

相关实验视频

Updated: Sep 10, 2025

Author Spotlight: Advancing the Analysis of Plasma Extracellular Vesicle Proteome for Cardiovascular Biomarker Studies
05:30

Author Spotlight: Advancing the Analysis of Plasma Extracellular Vesicle Proteome for Cardiovascular Biomarker Studies

Published on: January 31, 2025

606

皮炎风险分层的血蛋白质特征

Thomas E Ueland1, John P Shelley1, Jonathan D Mosley2

  • 1Vanderbilt University School of Medicine, Nashville, Tennessee.

The Journal of surgical research
|August 24, 2025
PubMed
概括
此摘要是机器生成的。

血蛋白质谱增强了分泌体炎风险分层. 将蛋白质组数据与遗传和生活方式因素相结合,可以提高严重膜炎的预测准确度,从而有助于临床管理.

关键词:
脊椎疾病脑炎整个现象的关联研究多基因风险评分精准医学蛋白质组学

更多相关视频

A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions
09:00

A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions

Published on: April 18, 2025

829
Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
14:48

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

7.1K

相关实验视频

Last Updated: Sep 10, 2025

Author Spotlight: Advancing the Analysis of Plasma Extracellular Vesicle Proteome for Cardiovascular Biomarker Studies
05:30

Author Spotlight: Advancing the Analysis of Plasma Extracellular Vesicle Proteome for Cardiovascular Biomarker Studies

Published on: January 31, 2025

606
A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions
09:00

A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions

Published on: April 18, 2025

829
Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
14:48

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

7.1K

科学领域:

  • 胃肠病学
  • 蛋白质组学
  • 遗传学

背景情况:

  • 皮炎风险分层传统上依赖于生活方式因素.
  • 新出现的证据表明分子特征在预测管炎风险方面发挥了作用.

研究的目的:

  • 评估血蛋白质谱是否可以增加饮食和遗传因素对膜炎风险分层.
  • 开发和验证严重管炎的血蛋白质组风险评分.

主要方法:

  • 使用了英国生物库队列,其中包括一个用于得分推导的培训组和一个用于验证的测试组.
  • 差异表达和途径分析确定了关键蛋白质和途径.
  • 最小绝对收缩和选择器操作者回归模型计算了蛋白质学风险得分.
  • 考克斯回归模型评估了该得分的实用性以及人口,生活方式和遗传因素.

主要成果:

  • 来自151种蛋白质的蛋白质性风险得分与严重流炎的风险增加有关 (HR1. 48).
  • 与人口和生活方式因素相比,整合蛋白质和遗传因素显著改善了风险预测模型.
  • 全现象关联研究将高蛋白质组风险与功能障碍和心脏代谢特征联系在一起.

结论:

  • 血蛋白质谱为分泌体炎风险分层提供了有价值的补充信息.
  • 结合遗传和生活方式数据的蛋白质基因风险评分,提高了严重水炎的预测能力.
  • 这些研究结果表明,在管炎中可能有新的诊断和治疗策略.