2型糖尿病和心血管疾病患者的跌倒风险增加:系统性审查和分析
Aksayan Arunanthy Mahalingasivam1, Peter Vestergaard2,3, Nicklas Højgaard-Hessellund Rasmussen2,3
1Steno Diabetes Centre North Denmark, Aalborg University Hospital, Aalborg, Denmark. aksayan.mahalingasivam@rn.dk.
概括
患有2型糖尿病和心血管疾病的人面临更高的跌倒风险. 虽然这种联系是显而易见的,但导致该群体下降的特定心血管疾病需要进一步研究.
科学领域:
- 老年学
- 心脏病学
- 内分泌学
背景情况:
- 二型糖尿病 (T2D) 与跌倒风险的增加有关.
- 心血管疾病 (CVD) 进一步增加了T2D患者的跌倒风险.
- 对于T2D,心血管疾病和跌倒风险之间的具体相互作用尚不完全了解.
研究的目的:
- 系统地审查和对患有T2D和CVD同时存在的个体中跌倒风险的证据进行元分析.
- 估计与并发性T2D和CVD相关的跌倒风险的大小.
主要方法:
- 在PubMed,Embase和Cochrane数据库中进行系统的文献搜索,遵循PRISMA指南.
- 评估T2D患者患有或没有心血管疾病的跌倒风险的研究的元分析.
- 使用JADAD,NOS和GRADE工具进行质量评估.
主要成果:
- 与单独患有T2D的人相比,患有T2D和同时存在的心血管疾病的人的跌倒风险明显更高.
- 分析显示,心血管疾病的T2D患者的跌倒概率为1. 29 (95% CI为1. 03-1.63).
- 特定心血管疾病 (高血压,心力衰竭等) 之间的关联 没有确的结果.
结论:
- 同时存在的T2D和CVD与跌倒的患病率增加有关.
- 目前的证据不足以确定特定心血管疾病与T2D患者的跌倒风险之间的确切因果关系.
- 需要进一步的研究来澄清这种人口减少的机制和具体因素.
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