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Updated: May 4, 2026

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
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一个小说. 对MAPT/Tau传播的elegans模型揭示了对内解体完整性和种子MAPT/Tau聚合至关重要的基因

Carl Alexander Sandhof1,2, Nicole Martin3, Jessica Tittelmeier3

  • 1Center for Molecular Biology of Heidelberg University (ZMBH) and German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Heidelberg, Germany.

Autophagy
|August 25, 2025
PubMed
概括

研究人员确定了维护内分泌体完整性的细胞通路, 这对于防止MAPT/Tau病理在阿尔茨海默氏症等神经退行性疾病中传播至关重要.

关键词:
阿尔茨海默病细胞内解体系统溶酶体膜通透性神经退行症类似的扩散病症

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