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Updated: May 8, 2026

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry UPLC-HRMS
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Published on: May 20, 2013

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基于UPLC-LCMS的方法开发,验证,强制降解和尼罗加斯塔特药物质的杂质分析

S R Thrinath1, Manikandan Krishnan1, K S Lakshmi1

  • 1Department of Pharmaceutical Analysis, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur - 603203, Tamil Nadu, India.

Current topics in medicinal chemistry
|August 25, 2025
PubMed
概括

一种新的UPLC-MS方法可靠地确定Nirogacestat在应力条件下的稳定性和杂质. 这种验证的测定对于药品质量控制和法规遵守至关重要,确保药物的安全性和有效性.

关键词:
强迫退化研究污染情况分析方法验证尼罗加塞塔特稳定性指示试验UPLC-LCMS 方法

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