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在声波辐射力成像中使用循环线圈模拟聚焦超声波

Kristen Zarcone¹, Anuj Sharma¹, William A Grissom¹

¹Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.

Magnetic resonance in medicine

|August 25, 2025

概括

一个新型的脉冲直流环线圈有效地模拟了体内声波辐射力 (ARF) 的位移. 这项创新有助于在没有跨超声波挑战的情况下开发MR-声波辐射力成像 (MR-ARFI).

科学领域:

生物医学工程
医学成像
物理

背景情况:

用MR-声波辐射力成像 (MR-ARFI) 能够进行非侵入性组织特性映射.
目前的MR-ARFI开发面临着跨超声波设置的挑战,包括监管,声学和硬件限制.

研究的目的:

开发一种方法来模拟MR-ARFI中的超声波诱导的位移,而无需使用实际的跨超声波.
使MR-ARFI技术在人类身上更容易开发和测试.

主要方法:

使用相对照成像检测脉冲超声波引起的焦点组织移位.
一个定制的脉冲直流循环线圈被开发来模拟超声波诱导的相位变化.
通过对MR-ARFI进行模拟和体内志愿者实验来确定线圈的性能.

主要成果:

构建的循环线圈准确地模拟了非共振场图,与模拟预测密切匹配.
卷轴的焦点尺寸 (全宽半最大) 在场地图上测量在22.7毫米,与模拟一致.
在体内实验表明,该线圈产生相当于3.5μm的相位移,验证了其在MR-ARFI中的功能.

结论:

一个脉冲直流循环线圈可以成功地复制声波辐射力诱导的位移.
这种线圈为开发MR-ARFI方法提供了可行的替代方案,克服了跨超声波的局限性.

关键词:

其他国家聚焦式超声波

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