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Updated: Jun 10, 2026

Sample Extraction and Simultaneous Chromatographic Quantitation of Doxorubicin and Mitomycin C Following Drug Combination Delivery in Nanoparticles to Tumor-bearing Mice
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用LC-MS/MS方法对多克索鲁比辛和皮佩林进行共同估计:配方开发和药理动力学研究

Pooja Yadav1,2, Divya Chauhan1,2, Pavan Kumar Yadav1,2

  • 1Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, India.

Bioanalysis
|August 25, 2025
PubMed
概括

这项研究开发了固体脂质纳米颗粒 (SLN) 用于口服计量化疗,同时提供多克索鲁比辛 (DOX) 和皮佩林 (PIP). 这些SLN增强了药物的生物可用性和降低了毒性,显示了改善癌症治疗的前景.

关键词:
一个LC-MS/MS生物分析方法的验证多克索鲁比辛药物动力学研究皮佩林固体脂质纳米粒子

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