使用患者分割样本进行质量保证:对初级保健实验室的建议
Anne Stavelin1, Eva Rønneseth1, Anne Lise Fossum1,2
1The Norwegian Organisation for Quality Improvement of Laboratory Examinations (Noklus), 72982 Haraldsplass Deaconess Hospital , Bergen, Norway.
Clinical chemistry and laboratory medicine
|August 25, 2025
概括
患者分样分析提高了初级医疗保健点检测 (POCT) 的质量保证. 这些用户友好的指导方针提供了明确的POCT和中央实验室结果比较,确保可靠的患者测试.
科学领域:
- 实验室医学
- 主要医疗保健质量保证
背景情况:
- 在初级医疗保健中采用临床检测 (POCT) 需要强有力的质量保证 (QA).
- 患者分样方法 (将POCT与中央实验室结果进行比较) 是一个有价值的质量保证工具.
- 在初级医疗保健中实施患者分样分析的实际指导是有限的.
研究的目的:
- 为初级医疗保健中非实验室人员制定用户友好的建议.
- 提供关于何时以及如何进行患者分样比较的明确指导.
- 为比较POCT和中央实验室结果确定可接受的限值.
主要方法:
- 一个专家小组根据文献审查和专业经验提出了建议.
- 使用多种方法确定实用性可接受性极限.
- 通过涉及120多名员工的审计来完善建议.
主要成果:
- 如果没有EQA程序,内部QC不足,或POCT结果与临床预期相冲突,建议对患者进行分组样本比较.
- 结果比较的可接受限值为15%或20%,取决于测量值.
- 建议使用结构化的检查清单来审查这些限制之外的结果.
结论:
- 这些代表了首次发表的,易于使用的关于在初级医疗保健中使用患者分样的建议.
- 这些指导方针旨在简化非实验室人员的实施.
- 预计这些质量保证程序的广泛采用将提高POCT的可靠性.
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