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Updated: Sep 10, 2025

Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells
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Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells

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聚合IgA单克隆性门病模拟双克隆性门病:一个病例报告

Kadija Mefire1, Ouissam El Mohtarim1, Samira El Machtani Idrissi1

  • 1Biochemistry-Toxicology Laboratory, Faculty of Medicine and Pharmacy, Mohammed V Military Training Hospital, Mohammed V University, Rabat, MAR.

Cureus
|August 25, 2025
PubMed
概括

血清蛋白电泳的两个单克隆带可能表明双克隆性胃病变. 然而,这种情况表明IgAlambda可以形成多重聚合物,模仿双克隆性. 甲基甲基乙醇证实了单个单克隆IgA羔羊成分.

关键词:
双克隆性胃病变毛细血管电泳单克隆性牙病变有关蛋白质聚合免疫球蛋白a

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Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
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