细菌病和内血管感染:对100名患者的回顾性研究
Christopher V Radcliffe1, Melis N Anahtar2, Elizabeth L Hohmann3
1Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Open forum infectious diseases
|August 25, 2025
概括
在近三分之一的患者中,乳酸菌血症可能导致内心炎. 内心器械和注射药物使用增加了这种风险,强调需要仔细的临床解释阳性血液培养.
科学领域:
- 传染性疾病
- 微生物学
- 心脏病学
背景情况:
- 乳球菌是常见的胃肠道细菌,在血液培养物中发现时通常被认为是皮肤污染物.
- 然而,尽管罕见,但已经记录了乳杆菌的血液感染和内心炎.
研究的目的:
- 确定可能或确定的内心炎的预测因子.
- 分析血液培养中的Lactobacillus分离物的临床意义.
主要方法:
- 在22年内进行了回顾性队列研究.
- 使用修改的杜克标准分析了患有Lactobacillus细菌性/内血管感染的患者.
- 血液培养污染 (BCC) 被排除在外;通过微稀释来确定抗菌敏感性.
主要成果:
- 在331名确定的患者中,包括100名患者在分析中.
- 29% 的患者出现可能或确定的内心炎.
- 内心器械/非本源门 (RR, 8. 57) 和注射药物使用 (RR, 13. 47) 是显著的预测因素.
- 90天的死亡率为22%.
结论:
- 近三分之一的乳杆菌病患者患有内心炎.
- 多微生物感染很常见.
- 血液培养中的乳酸菌应被视为潜在的致病物,需要临床背景进行解释.
相关概念视频
Endocarditis I: Introduction
26
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
26
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.4K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.4K
Endocarditis II: Clinical Features of Infective Endocarditis
25
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
25
Endocarditis III: Medical Management
17
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
17
Endocarditis IV: Nursing Management
27
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
27
Acute Pyelonephritis II: Diagnostic Studies and Management
40
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
40


