儿科门静脉洞形转变的管理:一个七例单中心研究
Zhida Chen1, Hui Liu1, Wanfu Li1
1First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang, China.
Frontiers in pediatrics
|August 25, 2025
概括
在儿童中,孔腔静脉转换 (CTPV) 可以通过Rex分离或肝移植有效地治疗. 这两种手术都能改善患者的血液循环,
科学领域:
- 儿童手术
- 血管外科手术
- 肝病学
背景情况:
- 门静脉洞穴转化 (CTPV) 是儿童肝前门高血压的主要原因.
- 雷克斯分离器重建肝脏门路, 降低压力, 恢复血液流动, 促进生长.
- 活体供体肝脏移植是CTPV患者不适合Rex分离的最终治疗方法.
研究的目的:
- 总结治疗儿科门静脉洞形变化的临床疗效和机构经验.
- 评估儿童中CTPV治疗的外科结果和长期结果.
主要方法:
- 在2021年12月至2025年3月期间接受CTPV治疗的七名儿科患者的回顾性分析.
- 手术前的评估包括多普勒超声波和CTA血管学.
- 治疗包括六次活体供体肝移植和一次雷克斯分流手术.
主要成果:
- 在3 - 42个月的随访期间,所有7次手术均成功,没有胃肠道出血.
- 接受肝移植的患者没有出现排斥或重大并发症;Rex分离患者也有积极的结果.
- 在手术后观察到门静脉压力显著降低和全细胞减小 (P < 0. 05).
结论:
- 雷克斯分流是儿童中CTPV治疗的黄金标准.
- 活体捐赠者的肝脏移植对于不适合Rex转移的患者来说是一个重要的替代方案.
- 这两种干预都能恢复生理门脉循环,改善长期结果.
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