婴儿支气管炎后复发性喘息的危险因素:在中国进行了为期6年的单中心后续研究
Sainan Chen1, Xueyun Xu1, Min Wu1
1Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, China.
Frontiers in pediatrics
|August 25, 2025
概括
患有呼吸道综合体病毒 (RSV) 支气管炎和史前的婴儿面临更高的复发性喘息风险. 这项研究确定了儿童支气管炎后喘息的关键危险因素.
科学领域:
- 儿童肺病学
- 免疫学
- 流行病学
背景情况:
- 诊断为支气管炎的婴儿患有复发性喘息和喘的风险增加.
- 有助于重复喘息或喘的婴儿支气管炎后风险因素尚未完全理解.
- 这项前性观察研究旨在确定这些关键风险因素.
研究的目的:
- 在婴儿的第一个支气管炎发作后,确定其反复喘息和喘的危险因素.
- 调查儿童早期支气管炎的长期结果.
- 关联早期生活因素与晚期呼吸系统健康.
主要方法:
- 这项前性观察研究涉及89名患有第一个支气管炎的婴儿.
- 血清细胞因子分析和6年的随访,以追踪喘息发作.
- 在6-7岁时进行肺功能检测,总IgE和过敏原特定IgE.
主要成果:
- 72名婴儿完成了6年的随访;31. 9%的婴儿出现了复发性喘息,12. 5%的婴儿出现了喘.
- 患有支气管炎的婴儿,特别是患有呼吸道同胞病毒 (RSV) 和有史以来湿疹的婴儿,出现重复的学前喘息率显著增加.
- 在患有或没有目前喘的患者之间没有观察到血清细胞因子水平的显著差异.
结论:
- 婴儿时的支气管炎住院与六岁时出现复发性喘息和喘的严重风险有关.
- 呼吸道综合体病毒 (RSV) 支气管炎和同时存在的湿疹被认为是儿童复发喘息的关键危险因素.
- 早期识别这些风险因素可以帮助制定有针对性的干预措施和管理策略.
相关概念视频
01:29Asthma-I: Introduction
2.8K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.8K
01:17Pulmonary Cycle: Exhalation
1.8K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.8K
01:26Asthma-II: Pathophysiology and Classification
2.8K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.8K
01:20Asthma: Pathogenesis and Management
581
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
581
01:24Asthma-III: Symptoms and Complications
2.6K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.6K
01:22Chronic Obstructive Pulmonary Disease
1.4K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.4K