与自身免疫性风湿性疾病相关的间歇性肺病:来自土耳其的经验
Cemal Bes1, Fatih Yildirim1, Ramazan Eren2
1Department of Rheumatology, University of Health Sciences, Başakşehir Çam and Sakura City Hospital, İstanbul, Türkiye.
European journal of rheumatology
|August 25, 2025
概括
系统性硬化仍然是自身免疫性类风湿性疾病 (ARD) 患者间间歇性肺病 (ILD) 的主要原因. 在ARD-ILD病例中观察到的最常见的放射性模式是非特异性间歇性肺炎 (NSIP).
科学领域:
- 关节病学
- 肺病学
- 免疫学
背景情况:
- 间歇性肺病 (ILD) 在自身免疫性风湿性疾病 (ARD) 中带来了重大挑战,导致高发病率和死亡率.
- 了解ARD相关的ILD (ARD-ILD) 的特征对于有效管理至关重要.
研究的目的:
- 描述ARD-ILD患者的人口统计,血清学和放射学发现.
- 确定与ILD相关的最常见的类风湿性疾病和放射性模式.
主要方法:
- 进行了一项描述性的回顾性研究.
- 从患者病历中收集了人口统计,临床,实验室,放射学和组织病理学的数据.
主要成果:
- 评估了212名ARD- ILD患者,81. 1%为女性.
- 系统性硬化 (53. 8%) 是最常见的ARD,其次是类风湿性关节炎 (22. 2%).
- 非特异性间歇性肺炎 (NSIP) (71. 7%) 是主要的放射性模式,其次是通常的间歇性肺炎 (UIP) 模式 (22. 2%). 还发现了具有自身免疫特征的间歇性肺炎 (IPAF).
结论:
- 系统性硬化是ARD中ILD的主要驱动因素,NSIP是最常见的放射性表现.
- 具有自身免疫特征的间歇性肺炎 (IPAF) 是一种新出现的重要类型的ILD.
- 多学科合作对于诊断和管理复杂的ARD-ILD病例至关重要.
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