克服未确诊的呼吸道疾病:更多患有心血管并发症的患者是否应该接受阻塞性睡眠呼吸暂停的查?
Andrea Romarheim1,2, Sverre Lehmann2,3, Bjørn Bjorvatn4,5
1Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Expert review of cardiovascular therapy
|August 25, 2025
概括
阻塞性睡眠呼吸暂停 (OSA) 影响近10亿成年人, 尤其是心血管疾病患者. 早期查和干预对于治疗OSA和预防严重的心脏病至关重要.
科学领域:
- 心脏病学
- 睡眠医学
- 公共卫生
背景情况:
- 在全球范围内, 阻塞性呼吸暂停 (OSA) 诊断和治疗不足, 影响近10亿成年人.
- 由于异常症状和医疗障碍,OSA在患有心血管并发症的患者中非常普遍,导致诊断延迟.
- 没有治疗的OSA会加剧诸如抗性高血压,心房动,中风和心力衰竭等疾病.
研究的目的:
- 审查OSA与心血管健康之间的关系.
- 突出将OSA与心脏损伤联系在一起的病理生理机制.
- 强调更好的查工具对于早期OSA检测的重要性.
主要方法:
- 在PubMed的系统文献搜索.
- 对病理生理机制的审查.
- 对查和干预的专家共识的分析.
主要成果:
- 间歇性缺氧,自主调节失调和全身炎症是导致心脏病的关键机制.
- 建议对高危心血管患者进行常规的OSA查.
- 早期干预包括CPAP,改变生活方式和代谢风险管理.
结论:
- 将OSA评估纳入心脏病学实践可以提高检测率.
- 扩大诊断工具和早期干预可以减少与OSA相关的发病率,死亡率和医疗费用.
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