相关实验视频

Updated: Sep 10, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

对阻塞性睡眠呼吸暂停综合征的炎症标志物的评估

Yildiz Ucar¹, Aynur Sahin²

¹Department of Pulmonary Disease, Başkent University Faculty of Medicine, Ankara, Turkey.

Science progress

|August 25, 2025

概括

在严重阻塞性睡眠呼吸暂停综合征 (OSAS) 中,SII,SIRI,NLR和PIV等系统性免疫炎症指数升高. 这些标记可以帮助评估OSAS的严重程度和预后.

科学领域:

肺病学
免疫学
血液学

背景情况:

阻塞性呼吸暂停综合征 (OSAS) 是一种常见的疾病,其特征在于睡眠期间重复出现上呼吸道崩.
系统性炎症在OSAS的病理生理学和进展中起作用.
新的系统性免疫炎症指数可以提供有关疾病严重性的见解.

研究的目的:

研究系统性免疫炎症指数与OSAS严重程度之间的关系.
评估系统性免疫炎症指数 (SII),系统性炎症反应指数 (SIRI),中性细胞与淋巴细胞比率 (NLR) 和泛免疫炎症值 (PIV) 作为OSAS预后标志物的潜力.

主要方法:

对263名OSAS患者进行了回顾性横截分析.
根据呼吸暂停指数 (AHI) 将患者分为轻度,中度和严重的OSAS.
使用常规血液学参数计算和比较SII,SIRI,NLR和PIV.

主要成果:

所有检查的炎症指数 (NLR,SII,SIRI,PIV) 在OSAS严重程度组之间显示出统计学上显著的差异.
与轻度和中度OSAS组相比,这些标志物在重度OSAS患者中显著增加 (p < .05).
结果表明系统性炎症升高与OSAS严重程度增加之间存在正相关性.

结论:

系统性免疫炎症指数 (SII,SIRI,NLR,PIV) 与OSAS的严重程度有关.
这些易于计算的标记可以作为评估OSAS严重程度和预后的有用工具.
这些指数可能有助于临床决策和定制OSAS患者的治疗策略.

关键词:

睡眠呼吸暂停生物标志物免疫系统发生炎症有障碍的

更多相关视频

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

相关概念视频

Sleep Apnea

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...

Tonsillitis I: Introduction

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.