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通过调节糖解和基因素乙化,ACLY促进NK细胞效应器功能

Hyogon Sohn1, Ana Kolicheski1, Jennifer Poursine-Laurent1

  • 1Department of Pediatrics, Division of Rheumatology and Immunology, Washington University in St Louis, St Louis, MO, United States.

Journal of immunology (Baltimore, Md. : 1950)
|August 25, 2025
PubMed
概括

ATP酸酶 (ACLY) 对于自然杀手细胞的功能至关重要. 缺乏ACLY会损害NK细胞的免疫力,但酸盐补充会恢复它们的效应功能,突出ACLY

关键词:
细胞激活细胞因子表观遗传学自然杀手细胞动物

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