患有血管炎的患者的心脏病
在PubMed上查看摘要
概括
此摘要是机器生成的。血管炎的心脏并发症不常见,但风险因素和心脏异常普遍存在. 建议对患有血管炎的患者进行系统查和多学科治疗.
科学领域
- 心脏病学
- 关节病学
- 系统性血管炎
背景情况
- 心脏干扰是已知的血管炎并发症,通常与患者的治疗结果较差有关.
- 关于血管炎患者结构性心脏病和心律失常的具体发病率的数据有限.
研究的目的
- 在被诊断患有各种形式的血管炎的患者中调查结构性和心律失常的发病率.
- 在一组血管炎患者中确定心血管风险因素和心脏异常.
主要方法
- 一个单一中心的研究涉及191名患有巨细胞动脉炎 (GCA),塔卡亚苏动脉炎 (TAK),多关节性动脉炎 (PAN),多关节性动脉炎 (GPA) 或多关节性动脉炎 (EGPA) 的患者.
- 心脏成像包括心声学 (70%) 和心磁共振 (11%).
- 对人口特征,基线并发症和治疗方案的分析.
主要成果
- 虽然严重的心脏并发症很少见,但心血管风险因素如高血压和脂质失调是常见的,特别是在GCA中.
- 在33%和40%的EGPA患者中,心磁共振显示左心室缩功能障碍和心肌纤维化.
- 在GCA患者中发生了急性心肌梗塞;冠状动脉动图显示干预需要因血管炎类型而异.
结论
- 很大一部分血管炎患者表现出心血管风险因素,心脏结构异常和心律失常.
- 尽管罕见的严重事件,系统的心脏查和多学科治疗对于血管炎患者至关重要.
- 早期发现和治疗心脏干扰可能会改善血管炎的结果.
相关概念视频
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...

