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Updated: Sep 10, 2025

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来自Garcinia multiflora的新型双:隔离和α-氨酶抑制特性

Li Hua Gong1, Si Yi Wei2, Zhi Lin Jiao1

  • 1The Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang, P. R. China.

Chemistry & biodiversity
|August 25, 2025
PubMed
概括

果多种植物的茎和叶子产生了七种双化合物,其中四种是新的. 这些化合物对α- 氨基酶具有强烈的结合,但只有两种在体外表现出弱酶抑制活性.

关键词:
格尔西尼亚多种植物双化合物酶抑制活性分子对接α-氨酸酶

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α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
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