Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Sulfur Assimilation01:20

Sulfur Assimilation

72
Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
72
Biosynthesis of Nucleic Acids01:28

Biosynthesis of Nucleic Acids

169
Nucleic acid biosynthesis is a fundamental biochemical process that produces the purine and pyrimidine nucleotides essential for DNA and RNA synthesis. This pathway maintains a balanced nucleotide pool, preventing imbalances that could jeopardize genetic integrity and cellular function. Given the crucial role of nucleotides, their synthesis is tightly regulated to ensure proper cellular homeostasis.Purine BiosynthesisThe biosynthesis of purine nucleotides begins with ribose-5-phosphate, a...
169
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

5.6K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.6K
DNA Replication02:40

DNA Replication

50.8K
DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied.  After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
Replication in Prokaryotes
DNA replication...
50.8K
Pedigree Analysis01:35

Pedigree Analysis

85.1K
Overview
85.1K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

3.6K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Modulation of surface charges of napin by enzymatic deamidation to improve its techno-functional properties.

Food chemistry·2026
Same author

Cold plasma treatment induces protein oxidation and nitration, but enhances protein digestibility.

Food chemistry·2026
Same author

Talin-tensin3 interactions regulate fibrillar adhesion formation and tensin3 phase separation.

The Journal of cell biology·2025
Same author

Deciphering structural variation upon biotinylation of biotin carboxyl carrier protein domain in Streptococcus pneumoniae.

International journal of biological macromolecules·2024
Same author

A perylenemonoimide-based fluorescent probe: ultrasensitive and selective tracing of endogenous peroxynitrite in living cells.

The Analyst·2023
Same author

Structural and mechanistic insights into modulation of α-Synuclein fibril formation by aloin and emodin.

Biochimica et biophysica acta. General subjects·2022

相关实验视频

Updated: Sep 10, 2025

In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions
08:14

In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions

Published on: July 17, 2019

12.8K

生物素:从DNA到饮食

Shivani Karalia1, Vinod Kumar Meena2

  • 1Department of Food Science, Faculty of Science, University of Copenhagen, Rolighedsvej, 1958 Frederiksberg C, Denmark.

The Journal of nutritional biochemistry
|August 25, 2025
PubMed
概括

生物素 (维生素B7) 对于新陈代谢至关重要,并非由人类制造. 它的独特特性为新的抗菌药物和疾病诊断提供了潜力.

科学领域:

  • 生物化学
  • 分子生物学
  • 营养科学

背景情况:

  • 生物素 (维生素B7/H) 是细胞代谢的重要水溶性辅因子,包括脂肪酸和氨基酸代谢.
  • 人类细胞不会合成生物,而是从饮食或肠道细菌中获取.
  • 推的每日摄入量因年龄而异,估计在5 - 35微克/天之间.

研究的目的:

  • 探索生物素在遗传学,医疗保健和饮食中的多方面的作用.
  • 提供从细胞到营养水平的生物研究的整体概述.
  • 突出生物素在药物开发和诊断方面的潜力.

主要方法:

  • 对生物的结构,代谢和应用的现有文献的审查.
  • 对生物素与代谢途径和蛋白质的相互作用进行分析.
  • 探索生物素对抗致病细菌和生物膜形成的潜力.

主要成果:

  • 生物素在生命领域的代谢作用表明了抗菌药物开发的潜力.
  • 生物素与阿维丁的高亲和力使其成为疾病诊断中的生物化学传感器候选者.
  • 生物素与脂质合成蛋白的相互作用表明它有可能破坏细菌细胞外基质.

更多相关视频

AirID-Based Proximity Labeling for Protein-Protein Interaction in Plants
08:36

AirID-Based Proximity Labeling for Protein-Protein Interaction in Plants

Published on: September 16, 2022

1.8K
Expression, Isolation, and Purification of Soluble and Insoluble Biotinylated Proteins for Nerve Tissue Regeneration
12:03

Expression, Isolation, and Purification of Soluble and Insoluble Biotinylated Proteins for Nerve Tissue Regeneration

Published on: January 22, 2014

33.7K

相关实验视频

Last Updated: Sep 10, 2025

In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions
08:14

In Vitro Biochemical Assays using Biotin Labels to Study Protein-Nucleic Acid Interactions

Published on: July 17, 2019

12.8K
AirID-Based Proximity Labeling for Protein-Protein Interaction in Plants
08:36

AirID-Based Proximity Labeling for Protein-Protein Interaction in Plants

Published on: September 16, 2022

1.8K
Expression, Isolation, and Purification of Soluble and Insoluble Biotinylated Proteins for Nerve Tissue Regeneration
12:03

Expression, Isolation, and Purification of Soluble and Insoluble Biotinylated Proteins for Nerve Tissue Regeneration

Published on: January 22, 2014

33.7K

结论:

  • 生物素在细胞代谢和人类健康中起着至关重要的作用.
  • 它独特的生化特性为新的治疗和诊断策略提供了机会.
  • 进一步研究生物的机制可以促进药物发现和疾病管理.