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Updated: Sep 10, 2025

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双链断端切除因子和WRN促进人类细胞中的线粒DNA合成

Szymon A Barwacz1, Katrine Lundgaard1, Wei Wu1,2

  • 1Center for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.

Nature communications
|August 25, 2025
PubMed
概括

分子DNA合成 (MiDAS) 使用DNA双链断裂修复因子在压力下完成复制. 针对这些因素, 如WRN, 可能提供新的癌症疗法.

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