围产期侮辱的尺寸和精神病类经验的发展轨迹
Eric R Larson1,2, Nicole R Karcher3, Alexandra B Moussa-Tooks4,5,6
1Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN, USA. ericlars@iu.edu.
围产期的侮辱,如药物暴露和产科并发症与青春期持续的精神病性经历有关. 早期识别有风险的儿童对于公共健康至关重要.
科学领域:
- 神经科学
- 发展心理学
- 公共卫生
背景情况:
- 包括产科并发症和药物暴露在内的围产期侮辱正在上升,
- 这些侮辱往往同时发生,使对其对精神病谱系表型的影响的研究复杂化.
- 数据驱动的方法可以组织这些侮辱并评估它们对青少年精神病的长期影响.
研究的目的:
- 确定围产期侮辱的数据驱动层面.
- 研究这些维度对青少年精神病类似经历的纵向影响.
- 了解围产期侮辱对儿童发展的公共卫生影响.
主要方法:
- 使用了来自青少年大脑认知发展 (ABCD) 研究的11,417名年轻人的数据.
- 采用探索性因子分析来推导31个围产病例的尺寸.
- 应用潜增长模型来评估侮辱维度对5年的精神病类经验轨迹的影响.
主要成果:
- 确定了围产期侮辱的六个方面:物质暴露,产科并发症,分娩并发症,产后挑战,父母年龄和医疗需求.
- 药物暴露,产科并发症和父母年龄与更高的基线精神病类似体验有关.
- 父母的年龄和医疗需求与精神病类似经历的急剧下降有关,而其他维度显示在第四年经历的稳定关联.
结论:
- 围产期侮辱的数据驱动尺寸与青春期早期的稳定,高度的精神病性经验轨迹有关.
- 这些发现强调了早期识别暴露于围产期侮辱的后代的重要性.
- 解决这些暴露可能有助于减轻与后期精神病理相关的公共卫生负担.
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