老年人中术后认知功能障碍的发生率:使用基于网络的蒙特利尔认知评估应用程序进行的前性队列研究
Panithi Pongraweewan1, Surapa Tornsatitkul2, Arunotai Siriussawakul1,3
1Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Scientific reports
|August 25, 2025
概括
手术后的认知功能障碍 (POCD) 影响了超过40%的老年人,心血管疾病是危险因素. 像Auto-MoCA这样的数字工具有助于评估, 几乎一半受影响的患者在3个月内恢复认知能力.
科学领域:
- 老年学
- 神经科学
- 手术的结果
背景情况:
- 泰国人口老龄化增加了手术的风险.
- 尽管影响生活质量和死亡率,但术后认知功能障碍 (POCD) 的诊断不足.
- 对于老年患者来说,早期发现和监测POCD至关重要.
研究的目的:
- 在术后1周使用Auto- MoCA应用评估POCD的发生率.
- 为了比较有POCD和没有POCD的患者特征.
- 在手术后3个月检查认知恢复模式.
主要方法:
- 在泰国曼谷进行前性描述性队列研究.
- 接受重大选择性手术的60岁以上的患者.
- 在基线,一周和3个月使用基于网络的蒙特利尔认知评估 (Auto- MoCA) 重复认知评估. 从基线下降≥2个点的POCD.
主要成果:
- 在手术后一周的111名患者中,POCD发病率为40. 5%.
- 在视觉空间,注意力,语言,抽象和定向领域观察到显著的认知下降.
- 在3个月后,85名患者中有40. 0%患有POCD,其中42. 9%的认知功能恢复.
结论:
- 在接受手术的老年人中,术后认知功能障碍 (POCD) 非常普遍.
- 心血管疾病是POCD的一个重要危险因素.
- 数字认知评估工具很有价值,近一半受影响的患者在3个月内康复,这表明需要进行干预研究.
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