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Updated: Sep 10, 2025

Detection of Copy Number Alterations Using Single Cell Sequencing
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DelSIEVE:单细胞DNA测序数据中的单核酸变异和缺失的细胞系学建模

Senbai Kang1, Nico Borgsmüller2,3, Monica Valecha4,5

  • 1Faculty of Mathematics, Informatics and Mechanics, University of Warsaw, Warsaw, Poland.

Genome biology
|August 26, 2025
PubMed
概括

通过精确模拟单细胞DNA测序数据中的缺失,改善了进化事件的检测,并将真正的生物信号与技术噪音区分开来.

关键词:
收购偏差纠正细胞细胞系重建大肠直肠癌删除单核酸变体单细胞DNA测序统计类遗传模型三重阴性乳腺癌

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