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Updated: Sep 10, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

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异黄基因在小鼠中选择性地刺激主要卫星重复转录

Thomas Fuhrmann1,2,3, Nicholas Shukeir1, Reagan W Ching1

  • 1Max Planck Institute of Immunobiology and Epigenetics (MPI-IE), Freiburg, Germany.

Epigenetics & chromatin
|August 26, 2025
PubMed
概括

一种饮食补充剂Genistein可以选择性地刺激小鼠的主要卫星重复 (MSR) 转录超过100倍. 这种效应与DNA拓和细胞循环进展的改变有关,这表明基因斯坦具有新的抗癌机制.

关键词:
抗癌药物DNA 拓酶基因斯坦增长的抑制不同染色素主要的卫星重复

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