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Updated: May 12, 2026

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
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具有快速组织集成的脊髓样脚手架增强脊髓神经修复

Baoshuai Bai1,2, Ruizhi Zhang1, Chi Zhang3

  • 1Department of Orthopaedics, Qilu Hospital of Shandong University, Shandong University Centre for Orthopaedics, Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, 250012, P. R. China.

Advanced materials (Deerfield Beach, Fla.)
|August 26, 2025
PubMed
概括

一个新的仿生支架促进神经干细胞分化和脊髓修复. 这种先进的支架可显著改善脊髓损伤后的运动,感觉和自主功能恢复.

关键词:
生物模拟脚手架多种微环境神经再生脊髓损伤脊髓再生

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...