在部和膝盖关节整形术后治疗静脉血栓塞
Alexander Postajian1, Edgmin Rostomian1, Alexander Abdou1
1Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, 91766, USA.
概括
在关节或膝关节置换术后预防静脉血栓栓塞 (VTE) 是至关重要的. 本综述探讨了全关节整形术患者的风险因素,检测和预防策略,包括药物和手术技术.
科学领域:
- 骨科手术
- 血管医学
- 药理学
背景情况:
- 静脉血栓栓塞 (VTE),包括深静脉血栓塞 (DVT) 和肺栓塞 (PE),是关节整形手术 (THA) 和膝关节整形手术 (TKA) 后的重要死亡原因.
- 全球越来越多的THA和TKA需要优化VTE预防策略 (血栓预防).
研究的目的:
- 对THA和TKA患者的风险因素,检测和预防的当前文献进行审查.
- 对比各种药物和机械血栓预防方法的疗效和安全性.
- 讨论手术进步对静脉突发症风险的影响.
主要方法:
- 对THA和TKA的VTE现有文献进行了全面的审查.
- 药理学药物的比较分析:阿司匹林,低分子量肝素,里瓦洛克萨班,阿皮克萨班和华法林.
- 评估机械方法和手术内因素 (麻醉,手术时间,带使用).
- 探索微创手术和机器人辅助手术技术.
主要成果:
- 有多种药物和机械干预措施可以预防静脉突发症.
- 包括微创手术和机器人手术在内的手术技术正在不断发展.
- 没有一个最佳的血栓预防方案是普遍确定的.
结论:
- 在THA和TKA之后,最佳的静脉瘤预防需要考虑个体患者的因素.
- 可能需要进一步的研究来完善个性化血栓预防策略.
- 如何平衡静脉突发症和出血风险仍然是一个关键挑战.
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