Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Autoimmune Disorders01:29

Autoimmune Disorders

671
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
671
Inflammatory Response I: Vascular and Cellular01:30

Inflammatory Response I: Vascular and Cellular

12.4K
The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
12.4K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

382
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
382
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

321
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
321
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

540
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
540
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

39
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
39

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

International expert consensus recommendations on standardised nomenclature of SSA/Ro (TROVE2/Ro60 and TRIM21/Ro52) autoantibodies in autoimmune diseases.

Annals of the rheumatic diseases·2026
Same author

B cell Maturation Antigen Targeted Chimeric Antigen Receptor T Cell Therapy for Refractory Systemic Lupus Erythematosus and Systemic Sclerosis.

Arthritis & rheumatology (Hoboken, N.J.)·2026
Same author

The decline of AA amyloidosis in familial Mediterranean fever is significant, but the story is not over.

Clinical and experimental rheumatology·2025
Same author

Comment on: Standardisation of the term "anti-Ro/SSA" in patients with Sjögren's disease and other disorders.

Clinical and experimental rheumatology·2024
Same author

Reply to: Addressing key missing variables in reproductive health studies in familial Mediterranean fever.

Clinical and experimental rheumatology·2024
Same author

2nd Familial Mediterranean Fever Meeting.

Clinical and experimental rheumatology·2024

相关实验视频

Updated: Sep 10, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

7.3K

自发炎性疾病中的血管炎

Emilie Bohbot1, Eldad Ben-Chetrit

  • 1Rheumatology Unit, Division of Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Current opinion in rheumatology
|August 26, 2025
PubMed
概括
此摘要是机器生成的。

自身炎症性疾病 (AID) 与血管炎有关,而这种情况往往被忽视. 识别这些不同的模式有助于早期诊断和量身定制的治疗,

关键词:
自发炎性疾病氨酸脱氨酶2的缺乏家庭地中海热病虚孔,E1酶,X结合,自身炎症,体质综合征血管炎

更多相关视频

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

5.1K
Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

10.6K

相关实验视频

Last Updated: Sep 10, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

7.3K
Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

5.1K
Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

10.6K

科学领域:

  • 免疫学
  • 关节病学
  • 遗传学

背景情况:

  • 自身炎症性疾病 (AIDs) 涉及天生的免疫系统失调.
  • 艾滋病患者的血管炎经常被误诊.
  • 自2016年以来的最新数据突出显示了新发现的综合征和见解.

研究的目的:

  • 探索自身炎症疾病与血管炎之间的关系.
  • 专注于最近发现的综合征和最新的数据.
  • 审查各种艾滋病的血管表现.

主要方法:

  • 最近出版的文献综述 (自2016年以来).
  • 血管炎艾滋病的临床,遗传和组织学特征的分析.
  • 讨论潜在的炎症途径和遗传突变.

主要成果:

  • 血管炎发生在各种艾滋病中,包括家族地中海热,DADA2,VEXAS和CAPS.
  • 血管干扰范围从皮肤发现到全身血管炎.
  • 机制包括IL-1β,NF-κB过度激活和新的遗传突变.

结论:

  • 在艾滋病中早期识别血管炎对于诊断至关重要,尤其是在非典型的病例中.
  • 对于疑似病例,建议进行基因检测.
  • 了解不同的模式可以指导生物药物或干细胞移植的管理,以获得更好的结果.