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大麻使用与年轻成年期心理和功能健康的变化有关:自述和头发分析的证据

Lydia Johnson-Ferguson^1,2, Michelle Loher¹, Laura Bechtiger¹

¹Jacobs Center for Productive Youth Development, https://ror.org/02crff812University of Zurich, Zurich, Switzerland.

Psychological medicine

|August 26, 2025

概括

年轻人经常使用大麻与心理健康和福祉的恶化有关. 这包括增加精神病的经历,内化症状,侵略性,以及整体幸福感的下降.

科学领域:

精神病学
药物成
发展心理学

背景情况:

大麻的使用在年轻人中很普遍.
很少有研究在社区样本中研究大麻使用对精神病理和幸福感的纵向影响.
这项研究利用自我报告的频率和客观的THC度来评估大麻暴露.

研究的目的:

调查年轻成年人大麻使用与随后心理病理和功能健康变化之间的预测关系.
在预测这些变化方面,将自我报告的大麻使用与客观的头发delta-9-tetrahydrocannabinol (THC) 度进行比较.
分析大麻暴露与诸如精神病性经历,物质使用,内化症状,侵略性,一般福祉和就业/教育状况等结果之间的关联.

主要方法:

在20岁和24岁的863名年轻成年人的社区样本中进行了评估.
大麻使用是通过自我报告的频率和THC/cannabinol (CBN) 度来实现的.
统计分析包括多个线性和逻辑回归模型,对基线特征和结果进行控制.

主要成果:

自我报告的大麻使用和头发THC水平都预测了不良结果.
观察到的负面变化包括精神病的增加,内化症状,侵略性和有问题的物质使用.
一般人的幸福感下降,没有工作,没有教育或培训的可能性增加.
综合暴露分数没有比单个措施提供更大的预测能力.

结论:

在年轻成年期经常使用大麻与精神病理结果的有害变化有关.
这些不良影响不管是通过自我报告还是通过头发分析来衡量,都是一致的.
调查结果强调了经常食用大麻对心理健康和功能轨迹的重大影响.

关键词:

美国大麻功能上的幸福头发的情况心理病理学年轻的成年

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