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Updated: Sep 10, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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基因素脱乙酶抑制剂沃里诺斯塔特与二氧化碳无水酶II和IX的脱结合

Mitchell C Gulkis1, James T Hodgkinson2, Céleste P Sele3

  • 1Department of Biochemistry and Molecular Biology, University of Florida, 1149 Newell Drive, Gainesville, FL 32610, USA.

Acta crystallographica. Section F, Structural biology communications
|August 26, 2025
PubMed
概括

一种癌症药物沃里诺斯塔特 (SAHA) 可能与碳酸无水酶 (CA) 结合,可能导致副作用. 这项研究揭示了SAHA.

关键词:
HDAC 抑制剂的使用萨哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈人类碳酸无水化物.在目标之外的绑定.这就是Vorinostat.

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