持续活跃的气管瘤是否需要大量的抗生素药物? 与结膜感染和抗克拉米迪亚抗体的发生率的比较,西省,赞比亚
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在PubMed上查看摘要
概括
此摘要是机器生成的。在赞比亚,持续性气管瘤的患病率很高,但克拉米迪亚气管炎感染和血清阳性很低. 这表明从大规模药物管理转向监控是可能的.
科学领域
- 眼科 眼科
- 传染性疾病
- 公共卫生
背景情况
- 在赞比亚西部省的Kaoma,Luampa和Nkeyema地区,持续活跃的气管瘤是特有病.
- 卷状炎症 (TF) 是活跃卷状瘤的一个关键指标.
研究的目的
- 在评估单元中比较TF患病率与结膜性甲状腺炎 (Ct) 感染和抗Ct血清阳性.
- 在持续活跃的气管瘤流行地区为控制气管瘤的公共卫生战略提供信息.
主要方法
- 进行了集群样本横截面调查.
- 在年龄≥1岁的住院患者中评估了气管瘤.
- 分别从1至5岁和1至9岁的儿童中采集了结膜片和干血斑.
- 使用PCR检测了克拉米迪亚虫DNA,并通过横流测定测量了Ct抗原Pgp3的抗体.
主要成果
- 1- 9岁儿童的TF患病率为9. 2%.
- 在1至5岁的儿童中,抗Pgp3血清流行率为1. 7%,血清转化率为0. 6/100人年.
- 在1至5岁的儿童中,结膜性甲状腺炎DNA的患病率为0%.
结论
- 虽然TF的流行表明需要大量药物,但PCR和血清学表明目前的克拉米迪亚甲状腺病毒传播最小.
- 这些发现支持从大规模药物管理转向基于监测的气管瘤控制方法.
- 与TF评估一起整合分子和血清指标对于管理持久性活跃气管瘤是有价值的.
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