Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

22
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
22
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

47
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
47
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

51
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
51
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

33
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
33
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

28
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
28
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

42
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
42

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Tetralogy of Fallot: electrophysiology-guided surgical ablation during pulmonary valve replacement.

European heart journal·2026
Same author

One-Year Outcomes of the First 1000 Patients Implanted With the Medtronic Micra AV Leadless Pacing System in France: The AV-CESAR Cohort Study.

Circulation. Arrhythmia and electrophysiology·2026
Same author

Quantification of Tricuspid Valve Regurgitation With 2D and 4D-Flow MRI: Comparison of Different Methods in Adult Patients With Ebstein's Anomaly.

Journal of magnetic resonance imaging : JMRI·2026
Same author

Correction: <i>BAG3</i>-related myofibrillar myopathy: focus on its cardiac involvement.

Frontiers in genetics·2026
Same author

Irritative ventricular tachycardia after transcatheter pulmonary valve replacement.

European heart journal. Case reports·2026
Same author

Strategies for preventing arrhythmic sudden death in adult congenital heart disease.

European heart journal supplements : journal of the European Society of Cardiology·2026

相关实验视频

Updated: Sep 10, 2025

A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish
08:09

A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish

Published on: June 7, 2018

9.9K

在婴儿中辅助途径介导的扩张性心肌病

Claire Bertail-Galoin1, Nabil Jbilou1, Victor Waldmann2

  • 1Felix Guyon Hospital Center, CHU La Réunion, Competence Center for Complex Congenital Heart Disease - M3C, Saint-Denis, France.

Cardiology in the young
|August 26, 2025
PubMed
概括

一个10个月大的婴儿通过治疗由辅助通路预激发引起的隔膜失调而解决了扩大心肌病. 通过消除前兴奋,弗莱卡尼德治疗使左心室功能正常化.

科学领域:

  • 儿童心脏病学
  • 电生理学
  • 心肌病研究

背景情况:

  • 在婴儿中, Septal 不同步会导致扩张性心肌病.
  • 附带途径可能导致心脏电气异常.
  • 预兴奋综合征可能表现得没有明显的心力衰竭.

研究的目的:

  • 描述与辅助通路预激发相关的婴儿扩张性心肌病病例.
  • 研究预兴奋对隔膜同步和心室功能的影响.
  • 评估弗莱卡尼德在治疗这种疾病中的有效性.

主要方法:

  • 一个10个月大的婴儿患有扩张性心肌病.
  • 电心电图 (ECG) 分析以确定预兴奋和失调.
  • 评估左心室的功能.
  • 用弗莱卡尼德进行治疗.

主要成果:

  • 这名婴儿患有扩张性心肌病,原因是右隔膜附带通路的左隔膜失调.
  • 没有观察到心房回转性心力衰竭.
  • 弗莱卡尼德治疗成功地消除了心电图上的升级前激发.
  • 在治疗后左心室功能正常化.
关键词:
附带路径心肌疾病左捆分支区块预激发

更多相关视频

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

3.7K
A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
05:14

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo

Published on: May 16, 2020

4.8K

相关实验视频

Last Updated: Sep 10, 2025

A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish
08:09

A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish

Published on: June 7, 2018

9.9K
Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

3.7K
A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
05:14

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo

Published on: May 16, 2020

4.8K

结论:

  • 在婴儿中,辅助途径介导的预激发会导致明显的隔膜失调和扩张性心肌病.
  • 早期诊断和针对性的抗心律失常疗法,如弗莱卡尼德,可以逆转心脏功能障碍.
  • 这一案例凸显了在儿童心肌病中考虑电生理异常的重要性.