以往交叉连接的角膜内角膜环段与处女角膜:多参数倾向得分匹配分析
Karim Kozhaya1, Jad F Assaf, Nasrine Anais El Salloukh
1Department of Ophthalmology, American University of Beirut Medical Center, Beirut, Lebanon.
Journal of cataract and refractive surgery
|August 26, 2025
概括
角膜内环段 (ICRS) 在眼中提供类似的视觉和折射改善,无论它们是否曾经经历过角膜交叉连接 (CXL). 这一发现在先前接受CXL治疗和未接受CXL治疗的眼睛组进行比较时是正确的.
科学领域:
- 眼科 眼科
- 角膜外科手术
- 视觉科学
背景情况:
- 角膜是一种渐进的角膜脱落,导致视力受损.
- 角膜内环段 (ICRS) 用于改善角质的视力.
- 角膜交叉连接 (CXL) 是一种阻止角质进展的治疗方法.
研究的目的:
- 将ICRS插入在经过角膜交叉连接 (CXL) 的角膜眼中的结果与没有经历过的眼睛进行比较.
- 在匹配的患者群体中评估ICRS植入后的视觉,折射,地形和异常变化.
主要方法:
- 一个回顾性病例系列包括198只轻度至中度角质眼睛进行ICRS插入.
- 使用倾向分数匹配 (PSM) 来创建具有和没有先前CXL的可比眼睛组.
- 在手术前和ICRS植入后6个月分析了视觉,折射,地形和异常数据.
主要成果:
- 在PSM之后,32个XXL眼睛与32个没有XXL眼睛相匹配.
- 在ICRS治疗6个月后,两组患者的视觉敏度,折射,地形和角膜异常均显著改善.
- 在CXL和非CXL组之间没有观察到有统计意义的改善幅度差异.
结论:
- 无论之前的CXL治疗如何,ICRS插入在角质眼中提供了可比的视觉和折射效果.
- 当患者与疾病严重程度相匹配时,ICRS的有效性不会因以前的CXL而降低.
- 这表明CXL和ICRS可以有效地结合或独立使用,具有类似的视觉结果.
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