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Updated: Sep 10, 2025

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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Published on: June 3, 2016

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通过高脂肪饮食对脂肪细胞中的雌激素受体进行表观遗传编程

Rui Wu1, Fenfen Li2, Shirong Wang2

  • 1School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.

JCI insight
|August 26, 2025
PubMed
概括

高脂肪饮食增加了白色脂肪组织中雌激素受体α (Esr1) 基因的DNA甲基化,恶化了炎症和胰岛素抵抗. 减少这种甲基化可以改善小鼠的代谢健康.

关键词:
脂肪组织内分泌学表观遗传学代谢过程肥胖问题

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