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Updated: Sep 10, 2025

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通过人工智能引导的过渡路径采样捕获的STIM1跨膜螺旋体二分化

Ferdinand Horvath1, Hendrik Jung2, Herwig Grabmayr3

  • 1Institute of Theoretical Physics, Johannes Kepler University Linz, 4040 Linz, Austria.

Proceedings of the National Academy of Sciences of the United States of America
|August 26, 2025
PubMed
概括

流体相互作用分子1 (STIM1) 蛋白质二元化是感应的关键. 人工智能引导的模拟揭示了三种不同的STIM1跨膜螺旋二元体配置,澄清了其机制.

关键词:
在STIM1中,TM-螺旋体的二分化在商店经营的入口.过渡路径采样 过渡路径采样

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