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Updated: Sep 10, 2025

Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy
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Published on: August 20, 2018

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原子分辨率相互作用调节FUS折叠RRM域的分离成模型CAPRIN1凝聚物

Rashik Ahmed1,2,3,4, Jeffrey P Bonin1,2,3, Julie D Forman-Kay3,4

  • 1Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.

Journal of the American Chemical Society
|August 26, 2025
PubMed
概括

这项研究揭示了折叠FUSRNA识别因子 (RRM) 蛋白如何与生物分子凝聚物中的CAPRIN1支架蛋白结合. 这些相互作用驱动选择性客户端丰富,并被CAPRIN1酸化破坏.

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