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Updated: May 9, 2026

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors
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儿科 (脑外) 固体瘤的免疫环境:免疫组织化学和单细胞RNA测序数据的系统审查和整合

Francisca J Bergsma1, Jan Koster2, Bob Baalman1

  • 1Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.

European journal of cancer (Oxford, England : 1990)
|August 26, 2025
PubMed
概括

儿童瘤具有不同的免疫细胞特征,与成年人相比,脑瘤具有较少的T细胞和更多的巨细胞. 这些发现对于开发有效的儿童癌症免疫疗法至关重要.

关键词:
免疫的景观免疫组织化学儿童固体瘤单细胞RNA测序系统审查

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.