孕产妇心力衰竭的危险因素和时间趋势:长达20年的基于人口的研究
Clara Kihlborg1, Jonas Faxén2, Maria Sennström3
1Medical Programme, Karolinska Institutet, Stockholm, Sweden.
JACC. Heart failure
|August 26, 2025
概括
在瑞典,孕妇心力衰竭的发病率在20年内上升了66%,其中一半的病例与心脏疾病有关. 虽然风险因素起作用, 但它们并不能完全解释这一趋势.
科学领域:
- 心脏病学
- 母亲健康
- 公共卫生
背景情况:
- 孕产妇心力衰竭 (HF) 在全球越来越令人担忧,瑞典的趋势尚不清楚.
- 孕产妇风险因素和相关心脏病对HF发病率的影响尚不清楚.
研究的目的:
- 确定2000年至2019年瑞典每年发生的母乳高血压.
- 确定相关的心脏病,风险因素,并评估风险因素变化对HF趋势的影响.
主要方法:
- 一项全国性队列研究使用瑞典医疗出生登记数据 (2000-2019) 分析了2,078,384例分娩.
- 通过与国家患者和死亡人数登记的联系,确定了母亲的HF病例.
- 多变量逻辑回归分析风险因素和发病率,按发病和心脏病状况分层.
主要成果:
- 在过去的20年中,孕产妇的HF发病率增加了66%,达到每1000例0.34例.
- 大约50%的孕产妇患有心脏病.
- 怀孕前并发症和怀孕并发症被确定为危险因素;流行率的变化部分解释了发病率的上升.
结论:
- 在瑞典,孕产妇高血压发病率的增加带来了重大临床挑战.
- 相关心脏病的高发病率需要提高对受影响妇女的认识和管理策略.
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