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Updated: Sep 10, 2025

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
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Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

Published on: June 26, 2019

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AZ14289671是一种高度选择性和穿透血脑屏障的不可逆转的TKI,针对EGFRExon20插入

Aisha M Swaih1, Sara Talbot1, Adriana Savoca2

  • 1Bioscience, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, UK.

Cell reports. Medicine
|August 26, 2025
PubMed
概括

一种名为AZ14289671的新药有望治疗具有特定EGFR突变的非小细胞肺癌 (NSCLC). 这种强大的氨酸激酶抑制剂 (TKI) 有效地向瘤,包括大脑转移,同时保护健康细胞.

关键词:
欧洲粮食基金在 NSCLCexon 20 的插入小分子抑制剂

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