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Updated: Sep 10, 2025

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
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瘤向和微环境调节的活体中性粒细胞上车增强瘤病毒治疗

Xu Zhao1, Hanwei Huang1, Mingyang Liu1

  • 1Department of Surgical Oncology and General Surgery, The First Hospital of China Medical University, 155 North Nanjing Street, Heping District, Shenyang 110001, China; Department of Pharmaceutics, School of Pharmacy, Fudan University and Key Laboratory of Smart Drug Delivery, Ministry of Education, Shanghai 201203, China; Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, China Medical University, Ministry of Education, 155 North Nanjing Street, Heping District, Shenyang 110001, China.

Cell reports. Medicine
|August 26, 2025
PubMed
概括

中性粒细胞可以利用瘤病毒 (OVs) 来增强瘤透和有效性. 这种策略对抗免疫抑制性中性粒细胞,减少T细胞疲劳,改善抗瘤反应.

关键词:
T细胞耗尽中性粒细胞癌症病毒瘤微环境

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