在膝关节或关节骨关节炎的老年人中,各种运动方式和剂量的比较有效性:贝叶斯网络和剂量反应元分析
Shudong Tian1, Zhide Liang2, Yingdanni Yu1
1School of Physical Education, Shandong University, Jinan 250061, China.
Archives of physical medicine and rehabilitation
|August 26, 2025
概括
有氧运动最能减轻疼痛,而弹性训练则能改善骨关节炎患者的功能. 有最佳的运动剂量,但证据的确定性低至中等,需要个性化护理.
科学领域:
- 老年学
- 关节病学
- 运动科学
背景情况:
- 骨关节炎 (OA) 是老年人常见的疾病,严重影响关节和膝关节的功能,并引起疼痛.
- 运动是治疗关节炎的基石, 但最佳方法和剂量仍在争论中.
研究的目的:
- 系统地比较不同类型和强度的运动对患有关节和/或膝关节关节炎的老年人的疼痛和功能结果的有效性.
主要方法:
- 在主要数据库中进行了全面的文献搜索,截至2024年12月.
- 包括84项随机对照试验 (RCT),涉及60岁以上的6,373名患有关节/膝关节关节炎的参与者.
- 用贝叶斯网络和剂量反应元分析来评估运动对疼痛和功能的影响.
主要成果:
- 有氧运动对减轻疼痛的益处最大 (SMD: -1.19).
- 灵活性训练在功能方面得到了最好的改善 (SMD: -1.07).
- 确定了"U形"的剂量反应曲线,最佳剂量为580METs-min/week用于疼痛和450METs-min/week用于功能;证据确定性范围从非常低到中等.
结论:
- 运动对骨关节炎的疗效取决于具体的疗法,处方剂量和测量结果.
- 确定最佳的运动策略和剂量可以为医疗保健提供者提供个性化治疗计划,以提高患者在OA管理中的结果.
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