眼过手术后角膜胀的风险:一个回顾性队列研究
Veronica Pentland1, Rachel A Martin2, Robert J Campbell2
1School of Medicine, Faculty of Health Science, Queen's University, Kingston, ON, Canada.
概括
眼排水装置 (GDD) 的角膜胀风险比眼切除术更高. 新的手术,如Xen和微创视眼手术 (MIGS) 的风险较低,多次手术增加了水风险.
科学领域:
- 眼科 眼科
- 眼外科手术的结果
- 角膜健康
背景情况:
- 视角水是眼光镜手术后可能出现的长期并发症.
- 识别风险因素和比较手术技术对于患者管理至关重要.
研究的目的:
- 为了比较各种青光眼过手术后的长期角膜胀风险.
- 确定手术后角膜胀的预测因素.
主要方法:
- 在20年内对245名患者进行的333只眼睛的回顾性队列研究.
- 分析直径切除术,青光眼排水装置 (GDD),Xen和微侵袭性青光眼手术 (MIGS).
- 使用了卡普兰-梅尔生存曲线和考克斯比例危险模型.
主要成果:
- 角膜开始的平均时间为6. 2年;5年,10年和15年无率分别为94. 2%,79. 5%和70. 8%.
- 与管切除术相比,GDD显示角膜胀的风险显著增加 (HR: 3.07).
- 之前的玻璃眼手术数量是角膜胀的最强预测因素 (HR: 2. 40).
结论:
- 与管切除术相比,光眼疏通装置与角膜胀的风险增加有关.
- Xen和MIGS似乎是预防角膜胀的低风险替代方案.
- 眼镜外科手术的累计数量是发展角膜的重要危险因素.
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