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多器官功能障碍评分用于评估患有严重发烧和血小板缩小综合征的患者
Jeong Rae Yoo1, Sang Taek Heo1, Misun Kim1
1Department of Internal Medicine, Jeju National University College of Medicine, Jeju, Republic of Korea; Department of Internal Medicine, Jeju National University Hospital, Jeju, Republic of Korea.
概括
严重发烧与血小板减少综合征 (SFTS) 是一种严重的传播疾病. 在入院时较高的多器官功能障碍评分 (MODS) 与SFTS患者的死亡率增加有很强的相关性.
科学领域:
- 传染性疾病
- 危急护理医学
- 公共卫生
背景情况:
- 严重发烧与血小板缺血综合征 (SFTS) 是一种由传播的病毒性疾病,死亡率很高.
- 多器官功能障碍评分 (MODS) 是评估严重疾病患者器官功能障碍和预后的关键工具.
研究的目的:
- 研究多器官功能障碍评分 (MODS) 与诊断为SFTS的患者的临床结果之间的关联.
- 确定MODS是否可以作为SFTS严重程度和患者存活率的预后指标.
主要方法:
- 从2013年到2023年进行了一项观察性队列研究,包括被诊断患有SFTS的患者.
- 根据入院时的MODS和第7天的MODS,患者被分为四组:0-1,2,3,4-5和≥6.
主要成果:
- 该研究包括97名SFTS患者 (平均年龄为62. 4岁,男性为53. 6%).
- MODS ≥6与37. 5%的7天死亡率相关,而MODS 0-1的死亡率为0%.
- 患有MODS4-5的患者也表现出高7天死亡率 (25. 0%),较高的得分与死亡率,病毒载量和IL-6水平的增加显著相关.
结论:
- 多器官功能障碍评分 (MODS) 是衡量SFTS疾病严重性的一个有价值的预后工具.
- 持续监测MODS可以帮助早期识别需要积极干预的高风险患者,从而有可能改善SFTS的结果.
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