在轻度认知障碍的帕金森病中数字认知训练的可行性和初步有效性:试点研究
Dongje Lee1, Hang-Rai Kim1, Yu Jeong Park2
1Rowan, Cheonan, Republic of Korea.
Journal of movement disorders
|August 26, 2025
概括
在患有轻度认知障碍的帕金森病患者中,数字认知训练显著改善了记忆力和语言流性. 在这群人群中, SUPERBRAIN 计划的可行性和有效性得到了证明.
科学领域:
- 神经学
- 数字疗法
- 认知科学
背景情况:
- 认知障碍是帕金森病 (PD) 的常见和衰弱的非运动症状.
- 目前对PD认知衰退的药物治疗方法有限,需要探索替代干预措施.
- 数字认知培训计划为认知康复提供了一个有前途的,
研究的目的:
- 评估SUPERBRAIN数字认知训练计划在改善帕金森病和轻度认知障碍 (PD-MCI) 患者的认知功能方面的有效性.
- 在PD-MCI患者群体中评估基于家庭的平板电脑认知训练干预措施的可行性和遵守性.
主要方法:
- 这是一项随机对照试验,涉及四个诊所的29名PD- MCI患者.
- 参与者被分配到12周的SUPERBRAIN干预组 (n=16) 或对照组 (n=7).
- 在干预期前后使用首尔神经心理查电池 (SNSB) 测量认知结果.
主要成果:
- 干预组在延迟的口语回忆 (首尔口语学习测试) 和口语流性 (受控口语词汇关联测试) 中显著改善.
- 在对照组中没有观察到显著的认知变化.
- 统计分析 (ANCOVA) 证实干预组的语言回忆延迟 (F=7.15,P=0.015,部分 η2=0.28).
结论:
- 对于患有PD-MCI的人来说, SUPERBRAIN数字认知训练计划是一个可行的干预措施.
- 基于家庭的数字认知训练可以有效地提高PD-MCI患者的特定认知功能,如记忆和口语流.
- 这种方法是解决帕金森病认知缺陷的可行非药物治疗策略.
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