基于虚拟现实的暗示暴露疗法减少了男性的心理渴望使用甲基胺障碍:随机对照试验
Qiuping Huang1,2, Xinxin Chen2, Xuhao Wang2
1Department of Psychology, School of Humanities and Management, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Translational psychiatry
|August 26, 2025
概括
虚拟现实 (VR) 疗法有效地减少了MUD患者对甲基胺的渴望. 基于VR的暗示暴露疗法 (CET) 和带有厌恶疗法 (CETA) 均显著降低了强化剂的渴望,而CETA也改善了药物拒绝的自我有效性.
科学领域:
- 精神病学
- 行为科学
- 临床心理学
背景情况:
- 心理渴望是甲基胺使用障碍 (MUD) 患者复发的关键因素.
- 虚拟现实 (VR) 为治疗提供了沉浸式环境.
- 线索暴露疗法 (CET) 的目的是通过暴露个人与药物相关的线索来减少渴望.
研究的目的:
- 评估基于VR的暗示暴露疗法 (CET) 和基于VR的暗示暴露与厌恶疗法 (CETA) 在减少甲基胺渴望方面的有效性.
- 评估这些VR干预对MUD男性注意力偏差,康复信心,拒绝药物的自我有效性,焦虑和抑郁的影响.
主要方法:
- 一项随机对照试验,涉及89名患有MUD的男性,分为VR-CET,VR-CETA或中性场景 (NS) 组.
- 干预包括8周的16次治疗.
- 测量的主要结果是增强性渴望和提示性渴望;二次结果包括心理和自我有效性测量.
主要成果:
- 与NS组相比,VR-CET和VR-CETA组的强化渴望显著减少.
- 在VR-CETA组中,药物拒绝的自我有效性显著改善.
- 与NS组相比,VR- CET组的焦虑显著减少.
结论:
- 基于VR的CET和CETA有效地减少了MUD男性的心理渴望.
- 虚拟现实干预措施,特别是CETA,可以提高拒绝药物的自我有效性.
- 基于VR的疗法为MUD治疗提供了安全和有前途的途径, 需要进一步的大规模研究.
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