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干扰素刺激的基因查确定了CCND3作为对新出现的高致病性班达病毒的宿主限制因子

Zhao Xu1,2, Zhenyu Jiang1,2, Kuan Feng1,3

  • 1State Key Laboratory of Virology and Biosafety and National Virus Resource Center, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.

Nature communications
|August 26, 2025
PubMed
概括

赛克林D3 (CCND3) 是一种强大的抗病毒药物,可以对抗严重发烧与血小板缩小综合征病毒 (SFTSV). 这种宿主蛋白通过向病毒核蛋白来抑制病毒复制,为抗病毒疗法提供了新的途径.

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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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